{"id":29189,"date":"2025-03-31T09:04:03","date_gmt":"2025-03-31T08:04:03","guid":{"rendered":"https:\/\/babywellnessfoundation.org\/news-approfondimenti\/starnuti-pianto-e-occhi-arrossati-il-linguaggio-del-neonato-sulle-sue-difese-immunitarie\/"},"modified":"2026-06-29T15:06:38","modified_gmt":"2026-06-29T14:06:38","slug":"sneezing-crying-and-red-eyes-the-newborns-language-of-immune-defense","status":"publish","type":"news-approfondimenti","link":"https:\/\/babywellnessfoundation.org\/en\/news-approfondimenti\/sneezing-crying-and-red-eyes-the-newborns-language-of-immune-defense\/","title":{"rendered":"Sneezing, Crying, and Red Eyes: The Newborn&#8217;s Language of Immune Defense"},"content":{"rendered":"<h5 style=\"background-color: #e8eff4; color: white; padding: 5px;\"><strong><span style=\"color: #006271;\">Newborn Defense Mechanisms Against Allergens<\/span><\/strong><\/h5>\n<p>During the first months of life, newborns are particularly vulnerable to allergens, substances capable of triggering an immune response. A newborn&#8217;s ability to defend against these agents is complex and involves multiple physiological and immunological systems. Although the neonatal immune system is still developing, <em><strong>the body possesses natural defense mechanisms that help protect against the harmful effects of allergens<\/strong><\/em>. While these mechanisms are not always sufficient to completely prevent allergic reactions, they play a fundamental role in the body&#8217;s initial response to these substances.<\/p>\n<p><img fetchpriority=\"high\" decoding=\"async\" class=\"alignnone wp-image-19821\" src=\"https:\/\/babywellnessfoundation.org\/wp-content\/uploads\/2025\/03\/Slide-16_9-8-300x169.jpg\" alt=\"\" width=\"1370\" height=\"772\" srcset=\"https:\/\/babywellnessfoundation.org\/wp-content\/uploads\/2025\/03\/Slide-16_9-8-300x169.jpg 300w, https:\/\/babywellnessfoundation.org\/wp-content\/uploads\/2025\/03\/Slide-16_9-8-1024x576.jpg 1024w, https:\/\/babywellnessfoundation.org\/wp-content\/uploads\/2025\/03\/Slide-16_9-8-768x432.jpg 768w, https:\/\/babywellnessfoundation.org\/wp-content\/uploads\/2025\/03\/Slide-16_9-8-1536x864.jpg 1536w, https:\/\/babywellnessfoundation.org\/wp-content\/uploads\/2025\/03\/Slide-16_9-8-100x56.jpg 100w, https:\/\/babywellnessfoundation.org\/wp-content\/uploads\/2025\/03\/Slide-16_9-8-120x68.jpg 120w, https:\/\/babywellnessfoundation.org\/wp-content\/uploads\/2025\/03\/Slide-16_9-8.jpg 1920w\" sizes=\"(max-width: 1370px) 100vw, 1370px\" \/><\/p>\n<h5 style=\"background-color: #e8eff4; color: white; padding: 5px;\"><strong><span style=\"color: #006271;\">The Neonatal Immune System: An Initial Protective Barrier<\/span><\/strong><\/h5>\n<p class=\"PDq2pG_selectionAnchorContainer\" data-start=\"855\" data-end=\"1311\">Although still immature, the newborn is born with an immune system equipped with innate defense mechanisms. These include immune cells such as <strong data-start=\"998\" data-end=\"1013\">macrophages<\/strong>, which recognize and destroy pathogens, and <strong data-start=\"1058\" data-end=\"1073\">neutrophils<\/strong>, which play an important role in protecting against bacterial and fungal infections. In addition, newborns benefit from <strong data-start=\"1194\" data-end=\"1217\">maternal antibodies<\/strong> transferred through the placenta, providing passive immunity during the first months of life.<\/p>\n<h5><\/h5>\n<h5 style=\"background-color: #e8eff4; color: white; padding: 5px;\"><strong><span style=\"color: #006271;\">Sneezing: A Physiological Response<\/span><\/strong><\/h5>\n<p class=\"PDq2pG_selectionAnchorContainer\" data-start=\"1360\" data-end=\"1909\">Sneezing is one of the newborn&#8217;s most common defense mechanisms against allergens. It is a reflex response designed to eliminate irritating or harmful substances from the upper airways. When a newborn is exposed to allergens such as <strong data-start=\"1593\" data-end=\"1619\">pollen, dust, or smoke<\/strong>, the body responds by increasing mucus production in the nose and stimulating the contraction of the respiratory muscles, facilitating the expulsion of these substances. Although sneezing does not always completely remove allergens, it remains an immediate and natural protective strategy.<\/p>\n<h5><\/h5>\n<h5 style=\"background-color: #e8eff4; color: white; padding: 5px;\"><strong><span style=\"color: #006271;\">Crying: A Sign of Discomfort<\/span><\/strong><\/h5>\n<p>Crying is one of the newborn&#8217;s physiological responses to physical and emotional discomfort. In the presence of allergens,<em><strong> crying may indicate that the infant is experiencing eye irritation, nasal discomfort, or breathing difficulties<\/strong><\/em>. Although crying itself is not a direct defense mechanism, it serves as an important warning signal that alerts parents and healthcare professionals, enabling them to promptly reduce allergen exposure or provide appropriate treatment.<\/p>\n<p>&nbsp;<\/p>\n<h5 style=\"background-color: #e8eff4; color: white; padding: 5px;\"><strong><span style=\"color: #006271;\">Red eyes<\/span><\/strong><\/h5>\n<p>Red eyes, or <strong data-start=\"2457\" data-end=\"2484\">allergic conjunctivitis<\/strong>, are common responses in infants exposed to allergenic substances. <em><strong>The inflammatory reaction occurring in the eye causes dilation of the blood vessels within the conjunctiva, leading to redness<\/strong><\/em>. In response, the newborn may also experience excessive tearing and itching. Although allergic conjunctivitis is generally not an immediate medical emergency, it should be carefully monitored and managed to prevent possible complications, such as secondary infections or persistent discomfort.<\/p>\n<h5><\/h5>\n<h5 style=\"background-color: #e8eff4; color: white; padding: 5px;\"><strong><span style=\"color: #006271;\">Immunological Defense Mechanisms<\/span><\/strong><\/h5>\n<p class=\"PDq2pG_selectionAnchorContainer\" data-start=\"40\" data-end=\"596\">In addition to the immediate physiological response, the newborn&#8217;s immune system reacts to allergens through a series of immunological processes. When an allergen enters the body, the immune system may develop an <strong data-start=\"253\" data-end=\"278\">IgE-mediated response<\/strong>, involving the production of <strong data-start=\"308\" data-end=\"363\">allergen-specific Immunoglobulin E (IgE) antibodies<\/strong>. These antibodies bind to <strong data-start=\"390\" data-end=\"404\">mast cells<\/strong> and <strong data-start=\"409\" data-end=\"422\">basophils<\/strong>, triggering the release of <strong data-start=\"450\" data-end=\"463\">histamine<\/strong> and other inflammatory mediators, which are responsible for allergic symptoms such as swelling, itching, and breathing difficulties. <strong data-start=\"598\" data-end=\"624\">IgE (Immunoglobulin E)<\/strong> is a type of antibody produced by the immune system that plays a fundamental role in allergic reactions.<br \/>\nIn newborns, this immune response is generally less pronounced than in adults because their immune system is still maturing. For this reason, the risk of developing long-term allergies may be reduced through <strong data-start=\"939\" data-end=\"992\">early, carefully controlled exposure to allergens<\/strong>, which can promote the normal adaptation and maturation of the immune system.<\/p>\n<p data-start=\"40\" data-end=\"596\">\n<h5 style=\"background-color: #e8eff4; color: white; padding: 5px;\"><strong><span style=\"color: #006271;\">Exposure and Immune Adaptation<\/span><\/strong><\/h5>\n<p class=\"PDq2pG_selectionAnchorContainer\" data-start=\"1115\" data-end=\"1227\">The newborn&#8217;s response to allergens is influenced by a combination of <strong data-start=\"1185\" data-end=\"1196\">genetic<\/strong> and <strong data-start=\"1201\" data-end=\"1218\">environmental<\/strong> factors. Very early exposure to certain allergens may, in some cases, trigger an immune response that could predispose the child to developing more severe allergic diseases later in life. Conversely, <em><strong>controlled exposure to low doses of allergens may encourage immune adaptation and contribute to reducing the likelihood of developing severe allergies during childhood and adulthood<\/strong><\/em>.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Newborn Defense Mechanisms Against Allergens During the first months of life, newborns are particularly vulnerable to allergens, substances capable of triggering an immune response. A newborn&#8217;s ability to defend against these agents is complex and involves multiple physiological and immunological systems. Although the neonatal immune system is still developing, the body possesses natural defense mechanisms [&hellip;]<\/p>\n","protected":false},"author":1447,"featured_media":29190,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"focus-approfondimento":[872],"focus-appartenenza":[901],"coauthors":[794],"class_list":["post-29189","news-approfondimenti","type-news-approfondimenti","status-publish","format-standard","has-post-thumbnail","hentry","focus-approfondimento-allergies","focus-appartenenza-cure-e-attenzioni-amorevoli-en"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v25.8 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Sneezing, Crying, and Red Eyes: The Newborn&#039;s Language of Immune Defense - Baby Wellness Foundation<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/babywellnessfoundation.org\/en\/news-approfondimenti\/sneezing-crying-and-red-eyes-the-newborns-language-of-immune-defense\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Sneezing, Crying, and Red Eyes: The Newborn&#039;s Language of Immune Defense - Baby Wellness Foundation\" \/>\n<meta property=\"og:description\" content=\"Newborn Defense Mechanisms Against Allergens During the first months of life, newborns are particularly vulnerable to allergens, substances capable of triggering an immune response. A newborn&#8217;s ability to defend against these agents is complex and involves multiple physiological and immunological systems. Although the neonatal immune system is still developing, the body possesses natural defense mechanisms [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/babywellnessfoundation.org\/en\/news-approfondimenti\/sneezing-crying-and-red-eyes-the-newborns-language-of-immune-defense\/\" \/>\n<meta property=\"og:site_name\" content=\"Baby Wellness Foundation\" \/>\n<meta property=\"article:modified_time\" content=\"2026-06-29T14:06:38+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/babywellnessfoundation.org\/wp-content\/uploads\/2025\/03\/Slide-16_9-8.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1920\" \/>\n\t<meta property=\"og:image:height\" content=\"1080\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"4 minutes\" \/>\n\t<meta name=\"twitter:label2\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data2\" content=\"valentina.lotito@inglesina.com\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/babywellnessfoundation.org\/en\/news-approfondimenti\/sneezing-crying-and-red-eyes-the-newborns-language-of-immune-defense\/\",\"url\":\"https:\/\/babywellnessfoundation.org\/en\/news-approfondimenti\/sneezing-crying-and-red-eyes-the-newborns-language-of-immune-defense\/\",\"name\":\"Sneezing, Crying, and Red Eyes: The Newborn's Language of Immune Defense - Baby Wellness Foundation\",\"isPartOf\":{\"@id\":\"https:\/\/babywellnessfoundation.org\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/babywellnessfoundation.org\/en\/news-approfondimenti\/sneezing-crying-and-red-eyes-the-newborns-language-of-immune-defense\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/babywellnessfoundation.org\/en\/news-approfondimenti\/sneezing-crying-and-red-eyes-the-newborns-language-of-immune-defense\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/babywellnessfoundation.org\/wp-content\/uploads\/2025\/03\/Slide-16_9-8.jpg\",\"datePublished\":\"2025-03-31T08:04:03+00:00\",\"dateModified\":\"2026-06-29T14:06:38+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/babywellnessfoundation.org\/en\/news-approfondimenti\/sneezing-crying-and-red-eyes-the-newborns-language-of-immune-defense\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/babywellnessfoundation.org\/en\/news-approfondimenti\/sneezing-crying-and-red-eyes-the-newborns-language-of-immune-defense\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/babywellnessfoundation.org\/en\/news-approfondimenti\/sneezing-crying-and-red-eyes-the-newborns-language-of-immune-defense\/#primaryimage\",\"url\":\"https:\/\/babywellnessfoundation.org\/wp-content\/uploads\/2025\/03\/Slide-16_9-8.jpg\",\"contentUrl\":\"https:\/\/babywellnessfoundation.org\/wp-content\/uploads\/2025\/03\/Slide-16_9-8.jpg\",\"width\":1920,\"height\":1080},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/babywellnessfoundation.org\/en\/news-approfondimenti\/sneezing-crying-and-red-eyes-the-newborns-language-of-immune-defense\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/babywellnessfoundation.org\/en\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Sneezing, Crying, and Red Eyes: The Newborn&#8217;s Language of Immune Defense\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/babywellnessfoundation.org\/#website\",\"url\":\"https:\/\/babywellnessfoundation.org\/\",\"name\":\"Baby Wellness Foundation\",\"description\":\"\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/babywellnessfoundation.org\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Sneezing, Crying, and Red Eyes: The Newborn's Language of Immune Defense - Baby Wellness Foundation","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/babywellnessfoundation.org\/en\/news-approfondimenti\/sneezing-crying-and-red-eyes-the-newborns-language-of-immune-defense\/","og_locale":"en_US","og_type":"article","og_title":"Sneezing, Crying, and Red Eyes: The Newborn's Language of Immune Defense - Baby Wellness Foundation","og_description":"Newborn Defense Mechanisms Against Allergens During the first months of life, newborns are particularly vulnerable to allergens, substances capable of triggering an immune response. A newborn&#8217;s ability to defend against these agents is complex and involves multiple physiological and immunological systems. Although the neonatal immune system is still developing, the body possesses natural defense mechanisms [&hellip;]","og_url":"https:\/\/babywellnessfoundation.org\/en\/news-approfondimenti\/sneezing-crying-and-red-eyes-the-newborns-language-of-immune-defense\/","og_site_name":"Baby Wellness Foundation","article_modified_time":"2026-06-29T14:06:38+00:00","og_image":[{"width":1920,"height":1080,"url":"https:\/\/babywellnessfoundation.org\/wp-content\/uploads\/2025\/03\/Slide-16_9-8.jpg","type":"image\/jpeg"}],"twitter_card":"summary_large_image","twitter_misc":{"Est. reading time":"4 minutes","Written by":"valentina.lotito@inglesina.com"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/babywellnessfoundation.org\/en\/news-approfondimenti\/sneezing-crying-and-red-eyes-the-newborns-language-of-immune-defense\/","url":"https:\/\/babywellnessfoundation.org\/en\/news-approfondimenti\/sneezing-crying-and-red-eyes-the-newborns-language-of-immune-defense\/","name":"Sneezing, Crying, and Red Eyes: The Newborn's Language of Immune Defense - Baby Wellness Foundation","isPartOf":{"@id":"https:\/\/babywellnessfoundation.org\/#website"},"primaryImageOfPage":{"@id":"https:\/\/babywellnessfoundation.org\/en\/news-approfondimenti\/sneezing-crying-and-red-eyes-the-newborns-language-of-immune-defense\/#primaryimage"},"image":{"@id":"https:\/\/babywellnessfoundation.org\/en\/news-approfondimenti\/sneezing-crying-and-red-eyes-the-newborns-language-of-immune-defense\/#primaryimage"},"thumbnailUrl":"https:\/\/babywellnessfoundation.org\/wp-content\/uploads\/2025\/03\/Slide-16_9-8.jpg","datePublished":"2025-03-31T08:04:03+00:00","dateModified":"2026-06-29T14:06:38+00:00","breadcrumb":{"@id":"https:\/\/babywellnessfoundation.org\/en\/news-approfondimenti\/sneezing-crying-and-red-eyes-the-newborns-language-of-immune-defense\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/babywellnessfoundation.org\/en\/news-approfondimenti\/sneezing-crying-and-red-eyes-the-newborns-language-of-immune-defense\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/babywellnessfoundation.org\/en\/news-approfondimenti\/sneezing-crying-and-red-eyes-the-newborns-language-of-immune-defense\/#primaryimage","url":"https:\/\/babywellnessfoundation.org\/wp-content\/uploads\/2025\/03\/Slide-16_9-8.jpg","contentUrl":"https:\/\/babywellnessfoundation.org\/wp-content\/uploads\/2025\/03\/Slide-16_9-8.jpg","width":1920,"height":1080},{"@type":"BreadcrumbList","@id":"https:\/\/babywellnessfoundation.org\/en\/news-approfondimenti\/sneezing-crying-and-red-eyes-the-newborns-language-of-immune-defense\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/babywellnessfoundation.org\/en\/"},{"@type":"ListItem","position":2,"name":"Sneezing, Crying, and Red Eyes: The Newborn&#8217;s Language of Immune Defense"}]},{"@type":"WebSite","@id":"https:\/\/babywellnessfoundation.org\/#website","url":"https:\/\/babywellnessfoundation.org\/","name":"Baby Wellness Foundation","description":"","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/babywellnessfoundation.org\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"}]}},"_links":{"self":[{"href":"https:\/\/babywellnessfoundation.org\/en\/wp-json\/wp\/v2\/news-approfondimenti\/29189","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/babywellnessfoundation.org\/en\/wp-json\/wp\/v2\/news-approfondimenti"}],"about":[{"href":"https:\/\/babywellnessfoundation.org\/en\/wp-json\/wp\/v2\/types\/news-approfondimenti"}],"author":[{"embeddable":true,"href":"https:\/\/babywellnessfoundation.org\/en\/wp-json\/wp\/v2\/users\/1447"}],"replies":[{"embeddable":true,"href":"https:\/\/babywellnessfoundation.org\/en\/wp-json\/wp\/v2\/comments?post=29189"}],"version-history":[{"count":3,"href":"https:\/\/babywellnessfoundation.org\/en\/wp-json\/wp\/v2\/news-approfondimenti\/29189\/revisions"}],"predecessor-version":[{"id":29193,"href":"https:\/\/babywellnessfoundation.org\/en\/wp-json\/wp\/v2\/news-approfondimenti\/29189\/revisions\/29193"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/babywellnessfoundation.org\/en\/wp-json\/wp\/v2\/media\/29190"}],"wp:attachment":[{"href":"https:\/\/babywellnessfoundation.org\/en\/wp-json\/wp\/v2\/media?parent=29189"}],"wp:term":[{"taxonomy":"focus-approfondimento","embeddable":true,"href":"https:\/\/babywellnessfoundation.org\/en\/wp-json\/wp\/v2\/focus-approfondimento?post=29189"},{"taxonomy":"focus-appartenenza","embeddable":true,"href":"https:\/\/babywellnessfoundation.org\/en\/wp-json\/wp\/v2\/focus-appartenenza?post=29189"},{"taxonomy":"author","embeddable":true,"href":"https:\/\/babywellnessfoundation.org\/en\/wp-json\/wp\/v2\/coauthors?post=29189"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}